Involvement of Microglia in RGC Injury Induced by IOP Elevation in a Rat Ex Vivo Model
Version 1This dataset supports the findings of the manuscript titled: "Involvement of microglia in retinal ganglion cell injury induced by IOP elevation in a rat ex vivo acute glaucoma model." In this study, we used a rat ex vivo model of acute intraocular pressure (IOP) elevation to investigate the role of microglia in retinal ganglion cell (RGC) injury. Our results demonstrate that pressure-induced activation of the TLR4-NLRP3 inflammasome cascade contributes to microglial proliferation and IL-1β p
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This dataset supports the findings of the manuscript titled: "Involvement of microglia in retinal ganglion cell injury induced by IOP elevation in a rat ex vivo acute glaucoma model." In this study, we used a rat ex vivo model of acute intraocular pressure (IOP) elevation to investigate the role of microglia in retinal ganglion cell (RGC) injury. Our results demonstrate that pressure-induced activation of the TLR4-NLRP3 inflammasome cascade contributes to microglial proliferation and IL-1β p