Data Sheet 1_Relationship between lacrimal gland changes and corneal parameters in patients with primary Sjögren’s syndrome and non-Sjögren’s syndrome-related dry eye.docx

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BackgroundPrimary Sjögren’s syndrome(pSS) is characterized as an autoimmune disorder mostly involving exocrine glands and pSS related dry eye (SSDE) contributes to a severe subtype of dry eye disease (DED). Emerging imaging tools for ocular surface evaluation such as lacrimal gland ultrasonography (LGUS) and in vivo confocal microscopy (IVCM) remain underutilized in diagnosing the SSDE. This study aims to investigate LGUS-IVCM correlations to map structural-functional relationships in SSDE patie

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BackgroundPrimary Sjögren’s syndrome(pSS) is characterized as an autoimmune disorder mostly involving exocrine glands and pSS related dry eye (SSDE) contributes to a severe subtype of dry eye disease (DED). Emerging imaging tools for ocular surface evaluation such as lacrimal gland ultrasonography (LGUS) and in vivo confocal microscopy (IVCM) remain underutilized in diagnosing the SSDE. This study aims to investigate LGUS-IVCM correlations to map structural-functional relationships in SSDE patie